OBJECTIVE: To describe the process of hearing rehabilitation after cochlear implantation in an adolescent with post-lingual hearing loss. CASE REPORT: A 16-year-old patient with profound bilateral sensorineural hearing loss following bacterial meningitis received a unilateral cochlear implant in the right ear, the only ear with cochlear patency allowing insertion of the electrodes. Weekly 50-minute speech therapy sessions started after cochlear implantation. Over an 18-month period, the speech therapy aimed at guiding and advising the patient/family to help them face the difficulties caused by hearing loss in adolescence, and focused on hearing rehabilitation to restore auditory skills, especially auditory and speech perception in quiet and in noise. At 3 months of use of the cochlear implant, the patient demonstrated 90% sentence recognition in quiet, at 7 months, he reached 96% sentence recognition in noise (S/R +10 dB), and at 18 months, the patient showed a significant improvement in sentence recognition in noise with the HINT test, reporting quiet 52.7 dB; noise −1.4. CONCLUSION: Auditory rehabilitation in post-lingual hearing loss was beneficial for restoration of complex auditory skills and good performance in speech perception in noise. Even in post-lingual hearing loss, the auditory rehabilitation process must be structured based on achievement of goals, with initial, intermediate, and final goals identified according to individual performance ability, and effective participation of the patient and the specialized professional.