INTRODUCTION: Nasal polypoid, asthma, intolerance to A.A.S and / or AINES are the Fernand Windal Syndrome. World statistics show that affects around 10% of asthmatics. Not exist or are mediated immunoglobulin antigen-antibody reactions. These patients have no family history of asthma. Diagnosis: Definitely this syndrome can be established by controlled challenge test with increasing doses of AAS and with a proper medical history. Clinical case: 67 years, female, known allergy to AINES, asthma treatment with salbutamol, DM II treated with hypoglycemic agents and hypertension treatment with antihypertensive drugs. Table of years of development of bilateral nasal obstruction with dominance to the left + bilateral watery rhinorrhea, nasal spray and treated with antihistamines without improvement of the framework. WEIGHT occasional frontal headache and facial denies fever. On physical examination, RA: FND and FNI: pink mucous, centered septum, turbinate cannot be assessed by reason of the presence of multiple masses polipoideas whitish in color occupying the two nasal cavities with a smooth surface that reaches the nasal vestibule. In the laboratory serum IgE 210mg/dl to 110mg/dl normal, rest in CLASS. Spirometry with an obstructive pattern. In TAC of SPN: centered septum slightly hypertrophic turbinate mucosa at the expense of all the paranasal sines busy. It is realized FESS + polypectomy is performed without complications in post-surgical controls, patients with good development. CONCLUSION: In all patients with nasal polyposis and late onset asthma should be suspected syndrome windal and thus achieve the correct diagnosis, treatment and inform the patient about its possible development / development.