The ridge galli is part of the ethmoid bone and thus may suffer penumatization process. Studies indicate that penumatization occurs between 3% and 14% of patients and is mainly due to cells of the ethmoid or frontal sinuses. OBJECTIVE: To describe two cases of galli ridge penumatization that evolved with the infectious process and was surgically treated by endoscopic techniques. MATERIAL AND METHODS: We selected two patients who sought care in otolaryngology in Blumenau / SC complaining of intense headache located. It was previously submitted to Otolaryngological examination and video-endoscopy. Computed tomography of the paranasal sinuses were identified with galli ridge penumatization thickening or opacification. Patients underwent medical treatment with antibiotics, corticosteroids, and no symptomatic improvement or recurrence of symptoms and maintaining radiographic changes. That said, the patients underwent drainage of the galli ridge through endoscopy. RESULTS: In the two cases were drained intraoperative mucopurulence penumatization of the galli ridge. There were no complications during and after surgery. All patients improved the clinical picture of headache postoperatively minimum of 1 year and 6 months. CONCLUSION: The penumatization of the galli ridge may be the victim of an infectious process simulating frames rhinosinusitis and showed little response to drug therapy, requiring endoscopic surgical treatment that has been proven safe and effective.