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Year: 2013  Vol. 17   Num. Suppl. 1  - Print:
THE RELATIONSHIP BETWEEN HEARING COMPLAINTS AND THE USE OF AMINOGLYCOSIDE IN THE TREATMENT OFPATIENTS WITH MULTIDRUG-RESISTANT TUBERCULOSIS IN RIO DE JANEIRO
Author(s):
Karla Anacleto de Vasconcelos, Afrânio Lineu Kritski, Antonio Ruffino Neto, Monica Kramer
Abstract:

OBJECTIVE: To identify the reporting auditory/vestibular complaints of among patients treated for multidrug-resistant tuberculosis (MDR-TB) in the last five 5years in the city of Rio de Janeiro and to analyze the relationship of these findings with the type of amino glycoside used. METHODS: There was carried out a secondary data collection were collected of from the medical records of patients treated for MDR-TB between the years 2006 to and 2010 in the state of Rio de Janeiro. The variables studied were the reports of hearing complaints such as hearing loss and tinnitus. The vestibular symptom of Dizziness was the vestibular symptom verified in this study. The reports on the interruption of amino glycoside treatment due to because of auditory or vestibular complaints, as well as and audiometric evaluation, were examined. RESULTS: A total of 599 records were analyzed, of which. In 172 records there were records of some reported patients with auditory or vestibular complaints after they had initiated initiation of treatment with amino glycosides. Thirty-six 36(20.9%) patients were advised to take an undergo audiometry or were referred to an otorhinolaryngologist. Twenty-four 24(66.6%) patients were examined, and only 4 patients had more than one audiometric evaluation, suggesting they had hearing follow--up. In 16Sixteen (6.6%) case patients there were found had some kind of hearing loss, with being 15(93.7% (15/16) of them having) of sensorineural type hearing loss that was (compatible with ototoxicity). The grade of hearing loss s ranged from mild to severe. All results had with descendent curves in all the results. Statistical There was a statistical association association was found between tinnitus and use of amino glycoside. CONCLUSION: The lack of information about auditory or vestibular complaints in patients treated with amino glycosides affects the observation of the real auditory condition of this population in the state Rio de Janeiro. The use of streptomycin and amikacin is associated with tinnitus.

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