INTRODUCTION: Reiter's syndrome is a spondyloarthropathy, which is one of the diseases known as reactive arthritis. It occurs as a non-supportive complication of an infection by lip polysaccharide producing bacterias such as Yersinia enterocolitica, Campylobacter jejune, and Chlamydia trachoma is. Its pathogenesis is unknown, but Reiter's syndrome is associated with the HLA-B27 gene. Its classic triad is defined as arthritis, conjunctivitis and urethritis. Other manifestations may also occur such as central and peripheral neuropathy, mucocutaneous lesions and heart issues such as pericarditis and valvular lesions. OBJECTIVE: To relate a possible association between Reiter's syndrome and sensor neural hearing loss. CASE: A patient presented with joint pain in the lumbar column, left knee, and left foot; conjunctivitis; and urethral discharge. Immuno fluorescence of the material from the urethra showed Chlamydia infection; therefore, Reiter's syndrome was diagnosed. Bone scintigraphy showed synovitis in the lumbar column and in the left knee. Blood work showed and increased erythrocyte sedimentation rate and C3 fraction of the complement. The patient complained of rapidly progressive hearing loss and tinnitus in the left ear a few days after the initial presentation. Audiometry showed severe sensorineural hearing loss in the left ear. Brainstem evoked response audiometry (BERA) demonstrated increased absolute latency on the left side. Magnetic resonance imaging (MRI) did not show any noteworthy findings; however, the MRI scan was performed 1 year after the acute phase of the disease. CONCLUSION: Because there is no study in the literature showing any correlation between Reiter's syndrome and hearing loss, we propose that an association could exist between them. We thus suggest that more studies be performed to get a better understanding of the association.