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Year: 2022  Vol. 26   Num. 3  - Julyy/Sept
DOI: 10.1055/s-0041-1724093
Original Article
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Association of Serum Calcium and Vitamin D with Benign Paroxysmal Positional Vertigo
Ron Jacob Thomas, M. K. Goutham, Vadisha Srinivas Bhat, Shrinath D. Kamath, Rajeshwary Aroor, Satheesh Kumar Bhandary
Key words:
benign paroxysmal positional vertigo - semicircular canal - otoconia - osteomalacia

Introduction Benign paroxysmal positional vertigo (BPPV) is one of the common disorders of the peripheral vestibular system. The prevalence of BPPV is found to be higher among middle-aged women.

Objectives To estimate the serum levels of calcium and vitamin D in patients with BPPV, and to study their association.

Methods The present is a hospital-based prospective case-control study. Venous blood samples of the 49 patients with BPPV and an equal number of age- and gender-matched individuals were recruited and submitted to an analysis of the serum levels of calcium and vitamin D.

Results Among the cases, 67.3% were found to be females, and 32.7% were males. Most of the 30 cases (61.3%) were aged > 40 years. The mean age of the cases was 44.39 years. The mean serum level of vitamin D in the cases was of 21.26 ng/ml compared with 17.59 ng/ml in the controls. The mean serum level of calcium was of 9.33 mg/dl in the cases, compared with 8.95 mg/dl in the controls. There was no significant difference in the serum levels of vitamin D and calcium between cases and controls.

Conclusion We could not establish any correlation between the serum levels of calcium and vitamin D with BPPV. However, a negative relationship was found between the serum levels of vitamin D and the number of episodes of BPPV (p = 0.012).



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