OBJECTIVE: To describe a patient with Lymphoma of medium line online media and literature review. CASE REPORT: A male patient of 54 years of age with a picture of three months to develop swelling at the top and bottom eyelid accompanied by the right eye proptosis and progressive decrease in the order of fifteen days before admission, feeling feverish, there a week weight loss, patients who smoke and elitist; physical examination: the right eye proptosis accompanied by chemosis and conjunctival injection, eye movements abolished, decreased visual acuity, anterior rhinoscopy to: FDN: observed numerous scabs who retire, purulent rhinorrhea, nasal endoscopy, granulomatosis tissue at the tail of the right middle and inferior turbinate, leaving necrotic material at the level of the middle meatus; takes place excerese Cadwell Luck combined with endoscopy, radiotherapy plus chemotherapy, pathological anatomy, malignancy high histological grade, immunohistochemistry, lymphoma of high grade malignancy. CONCLUSION: Lymphoma of the middle line is a category characterized by a destruction center-facial that begins in the nasal cavity. His primary diagnosis is different from Wegener's disease. Proofs of influence Computerized Tomography imaging of the paranasal sinuses for the precise study of the destruction. The treatment is based on radiation and chemotherapy, surgery is reserved for cases of tumors by their size, the radio and chemotherapy is not sufficient.