OBJECTIVE: To describe a patient with chondrosarcoma in nasal cavity and literature review. CASE REPORT: A female patient of 49 years of age coming from Villa Elisa, who is consulted by a frame of 5 years of development of mouth breathing and snoring, at first intermittent, then permanent, accompanied by watery rhinorrhea and casual feel ears plugged. 5 months is added to the framework of taste progressive bombment growth in the painful, accompanied by holocraneal headache intermittent heavy feeling face that subsides with common analgesics. CONCLUSION: although there are predictive factors for the development to the treatment of chondrosarcoma, many publications match the difficulty of predicting the same, largely due to the diversity of histological grade of the case described in the indicated treatment was applied, although the results were not the most desirable. It is imperative to find alternatives more specific and effective treatment of this disease and put as in many other cases our hope in genetic medicine to mediate a solution in the future.